Aeroallergen sensitization predicts acute chest syndrome in children with sickle cell anaemia

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Acute Chest Syndrome in Children with Sickle Cell Disease

Results: Our results revealed that the frequency of ACS episodes are age dependent, which occurred more frequently in young children, more than 4 years of age (n = 16) 57%. Fever and cough were the most frequent symptoms; (n = 26) 93 % and (n = 24) 86% respectively. Most of the cases experienced respiratory distress such as tachypnea (n = 24) 86%, chest retraction (n = 18) 64%, and decreased br...

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Acute Chest Syndrome in Children with Sickle Cell Disease

Acute chest syndrome (ACS) is a frequent cause of acute lung disease in children with sickle cell disease (SCD). Patients may present with ACS or may develop this complication during the course of a hospitalization for acute vaso-occlusive crises (VOC). ACS is associated with prolonged hospitalization, increased risk of respiratory failure, and the potential for developing chronic lung disease....

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Acute chest syndrome in sickle-cell disease.

25 consecutive episodes of acute chest syndrome in 13 adult patients with sickle-cell disease were studied retrospectively. Chest symptoms were present on admission in 23 of 25 episodes. Abnormal chest signs and an abnormal chest X-ray were present on admission in only 11 and 9 episodes, respectively, but developed later in the remainder. The 9 episodes with bilateral radiological changes were ...

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Acute Chest Syndrome of Sickle Cell Disease

Hospital Physician January 2007 15 T he acute chest syndrome (ACS) is an acute pulmonary illness that occurs in patients with sickle cell disease. ACS is currently defined as a new infiltrate on chest radiograph in conjunction with 1 other new symptom or sign: chest pain, cough, wheezing, tachypnea, and/or fever (> 38.5°C).1 The term acute chest syndrome was first suggested in 1979 by Charache ...

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Acute chest syndrome in adults with sickle cell disease.

STUDY OBJECTIVES Acute chest syndrome (ACS) is a frequent and potentially severe pulmonary illness in sickle cell disease (SCD). The aim of the study was to report the clinical features and outcome of consecutive ACS episodes in adult patients in a French SCD center. All patients were treated according to an uniform therapeutic protocol applying transfusion only in the more severe clinical form...

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2018

ISSN: 0007-1048

DOI: 10.1111/bjh.15076